Studies on Streptomyces Antibiotic, Cycloheximide. II. Naramycin-B, and Isomer of Cycloheximide.
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چکیده
منابع مشابه
Cycloheximide production by Streptomyces griseus: control mechanisms of cycloheximide biosynthesis.
Cycloheximide accumulation in a fermentation medium has been shown to be the product of the balance between synthesis and degradation of this antibiotic. Glucose has been shown to prevent cycloheximide degradation. Cycloheximide has been shown to interfere with its own synthesis probably due to feedback inhibition. Approaches for increasing cycloheximide titers in the light of these findings ar...
متن کاملUse of Cycloheximide
1. Effects of short-term and long-term administration of cycloheximide on rat liver mitochondrial protein synthesis have been examined and were found to be different. 2. Long-term administration of cycloheximide resulted in inhibition of total cellular protein synthesis including that of mitochondria while, at short-term intervals, 8 10 % of mitochondrial protein synthesis was cycloheximide-res...
متن کاملEffect of actidione (cycloheximide) on yeast fermentation.
Actidione, an antibiotic produced by Streptomyces griseus, is highly active against a large number of yeasts but it has no marked antibacterial activity. Of 22 species of yeasts tested by Whiffen (1948), 9 were completely inhibited by 0.17 jig drug per ml; Saccharomyces cerevisae required 10 ,ug per ml and 5 species were not inhibited by 1000 ,ug per ml. There appears to be little in the litera...
متن کاملA ction of cycloheximide on Zygosaccharomyces soja.
Tsukada, Yoji (Kyoto University, Kyoto, Japan), Tsunetake Sugimori, Kazutami Imai, and Hideo Katagiri. Action of cycloheximide on Zygosaccharomyces soja. J. Bacteriol. 83:70-75. 1962.-Cycloheximide is known to inhibit the growth of some species of Saccharomyces and other fungi. A new type of action of this antibiotic, with Zygosaccharomyces soja as the test organism, is described in this paper....
متن کاملA switch from cycloheximide-resistant consolidated memory to cycloheximide-sensitive reconsolidation and extinction in Drosophila.
It is generally accepted that, after learning, memories stabilize over time and integrate into long-term memory (LTM) through the process of consolidation, which depends on de novo protein synthesis. Besides, studies on several species have shown that reactivation of already stabilized LTM can either make this memory labile and then restabilize it (a process called reconsolidation) or inhibit i...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1959
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.7.27